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Abaloparatide, a novel PTH receptor agonist, increased bone mass and strength in ovariectomized cynomolgus monkeys by increasing bone formation without increasing bone resorption
SUMMARY: Abaloparatide, a novel PTH1 receptor agonist, increased bone formation in osteopenic ovariectomized cynomolgus monkeys while increasing cortical and trabecular bone mass. Abaloparatide increased bone strength and maintained or enhanced bone mass-strength relationships, indicating preserved...
Autores principales: | Doyle, N., Varela, A., Haile, S., Guldberg, R., Kostenuik, P. J., Ominsky, M. S., Smith, S. Y., Hattersley, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer London
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834552/ https://www.ncbi.nlm.nih.gov/pubmed/29260289 http://dx.doi.org/10.1007/s00198-017-4323-6 |
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