Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system

Given its high resistance, enhanced virulence, and high transmissibility, community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia is highly associated with high morbidity and mortality. Anti-virulence therapy is a promising strategy that bypasses the evolutionary pressur...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Niu, Chao, Ma, Bo, Xue, Xiaoyan, Li, Zhi, Chen, Zhou, Li, Fen, Zhou, Shan, Luo, Xiaoxing, Hou, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834619/
https://www.ncbi.nlm.nih.gov/pubmed/29500427
http://dx.doi.org/10.1038/s41419-018-0398-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834619/
https://www.ncbi.nlm.nih.gov/pubmed/29500427
http://dx.doi.org/10.1038/s41419-018-0398-z

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