Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density

B cells expressing high affinity antigen receptors are advantaged in germinal centers (GC), perhaps by increased acquisition of antigen for presentation to follicular helper T cells and improved T-cell help. In this model for affinity-dependent selection, the density of peptide/MHCII (pMHCII) comple...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, Chen-Hao, Nojima, Takuya, Kuraoka, Masayuki, Kelsoe, Garnett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834622/
https://www.ncbi.nlm.nih.gov/pubmed/29500348
http://dx.doi.org/10.1038/s41467-018-03382-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834622/
https://www.ncbi.nlm.nih.gov/pubmed/29500348
http://dx.doi.org/10.1038/s41467-018-03382-x

Ejemplares similares