Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

The identification of genes and regulatory elements underlying the associations discovered by GWAS is essential to understanding the aetiology of complex traits (including diseases). Here, we demonstrate an analytical paradigm of prioritizing genes and regulatory elements at GWAS loci for follow-up...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Zeng, Jian, Zhang, Futao, Zhu, Zhihong, Qi, Ting, Zheng, Zhili, Lloyd-Jones, Luke R., Marioni, Riccardo E., Martin, Nicholas G., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F., Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834629/
https://www.ncbi.nlm.nih.gov/pubmed/29500431
http://dx.doi.org/10.1038/s41467-018-03371-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834629/
https://www.ncbi.nlm.nih.gov/pubmed/29500431
http://dx.doi.org/10.1038/s41467-018-03371-0

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