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Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A

Bone metastatic lesions are classified as osteoblastic or osteolytic lesions. Prostate and breast cancer patients frequently exhibit osteoblastic-type and osteolytic-type bone metastasis, respectively. In metastatic lesions, tumor cells interact with many different cell types, including osteoblasts,...

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Detalles Bibliográficos
Autores principales: Hashimoto, Kyoko, Ochi, Hiroki, Sunamura, Satoko, Kosaka, Nobuyoshi, Mabuchi, Yo, Fukuda, Toru, Yao, Kenta, Kanda, Hiroaki, Ae, Keisuke, Okawa, Atsushi, Akazawa, Chihiro, Ochiya, Takahiro, Futakuchi, Mitsuru, Takeda, Shu, Sato, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834702/
https://www.ncbi.nlm.nih.gov/pubmed/29440427
http://dx.doi.org/10.1073/pnas.1717363115