NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host–Gut Microbiota Interactions during Inflammatory Bowel Disease

Interactions among the gut microbiome, dysregulated immune responses, and genetic factors contribute to the pathogenesis of inflammatory bowel disease (IBD). Nlrx1(−/−) mice have exacerbated disease severity, colonic lesions, and increased inflammatory markers. Global transcriptomic analyses demonst...

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Detalles Bibliográficos
Autores principales: Leber, Andrew, Hontecillas, Raquel, Tubau-Juni, Nuria, Zoccoli-Rodriguez, Victoria, Abedi, Vida, Bassaganya-Riera, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834749/
https://www.ncbi.nlm.nih.gov/pubmed/29535731
http://dx.doi.org/10.3389/fimmu.2018.00363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834749/
https://www.ncbi.nlm.nih.gov/pubmed/29535731
http://dx.doi.org/10.3389/fimmu.2018.00363

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