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Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans

Systems biology approaches have recently provided new insights into the mechanisms of action of human vaccines and adjuvants. Here, we investigated early transcriptional signatures induced in whole blood of healthy subjects following vaccination with a recombinant HIV-1 envelope glycoprotein subunit...

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Detalles Bibliográficos
Autores principales: Anderson, Jenna, Olafsdottir, Thorunn A., Kratochvil, Sven, McKay, Paul F., Östensson, Malin, Persson, Josefine, Shattock, Robin J., Harandi, Ali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834766/
https://www.ncbi.nlm.nih.gov/pubmed/29535712
http://dx.doi.org/10.3389/fimmu.2018.00301