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Metabolic Abnormalities Detected in Phase II Evaluation of Doxycycline in Dogs with Multicentric B-Cell Lymphoma

Doxycycline has antiproliferative effects in human lymphoma cells and in murine xenografts. We hypothesized that doxycycline would decrease canine lymphoma cell viability and prospectively evaluated its clinical tolerability in client-owned dogs with spontaneous, nodal, multicentric, substage a, B-c...

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Detalles Bibliográficos
Autores principales: Hume, Kelly R., Sylvester, Skylar R., Borlle, Lucia, Balkman, Cheryl E., McCleary-Wheeler, Angela L., Pulvino, Mary, Casulo, Carla, Zhao, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834767/
https://www.ncbi.nlm.nih.gov/pubmed/29536017
http://dx.doi.org/10.3389/fvets.2018.00025