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Metabolic Abnormalities Detected in Phase II Evaluation of Doxycycline in Dogs with Multicentric B-Cell Lymphoma
Doxycycline has antiproliferative effects in human lymphoma cells and in murine xenografts. We hypothesized that doxycycline would decrease canine lymphoma cell viability and prospectively evaluated its clinical tolerability in client-owned dogs with spontaneous, nodal, multicentric, substage a, B-c...
Autores principales: | Hume, Kelly R., Sylvester, Skylar R., Borlle, Lucia, Balkman, Cheryl E., McCleary-Wheeler, Angela L., Pulvino, Mary, Casulo, Carla, Zhao, Jiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834767/ https://www.ncbi.nlm.nih.gov/pubmed/29536017 http://dx.doi.org/10.3389/fvets.2018.00025 |
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