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Regulatory mechanisms of hypoxia‐inducible factor 1 activity: Two decades of knowledge

Hypoxia‐inducible factor 1 (HIF‐1) is a transcriptional activator of various genes related to cellular adaptive responses to hypoxia. Dysfunctions in the regulatory systems of HIF‐1 activity have been implicated in the pathogenesis of various diseases including malignant tumors and, thus, elucidatin...

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Detalles Bibliográficos
Autores principales: Koyasu, Sho, Kobayashi, Minoru, Goto, Yoko, Hiraoka, Masahiro, Harada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834787/
https://www.ncbi.nlm.nih.gov/pubmed/29285833
http://dx.doi.org/10.1111/cas.13483