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Cellular stress induces cancer stem‐like cells through expression of DNAJB8 by activation of heat shock factor 1

In a previous study, we found that DNAJB8, a heat shock protein (HSP) 40 family member is expressed in kidney cancer stem‐like cells (CSC)/cancer‐initiating cells (CIC) and that it has a role in the maintenance of kidney CSC/CIC. Heat shock factor (HSF) 1 is a key transcription factor for responses...

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Detalles Bibliográficos
Autores principales: Kusumoto, Hiroki, Hirohashi, Yoshihiko, Nishizawa, Satoshi, Yamashita, Masamichi, Yasuda, Kazuyo, Murai, Aiko, Takaya, Akari, Mori, Takashi, Kubo, Terufumi, Nakatsugawa, Munehide, Kanaseki, Takayuki, Tsukahara, Tomohide, Kondo, Toru, Sato, Noriyuki, Hara, Isao, Torigoe, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834799/
https://www.ncbi.nlm.nih.gov/pubmed/29316077
http://dx.doi.org/10.1111/cas.13501