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Identification of novel enriched recurrent chimeric COL7A1-UCN2 in human laryngeal cancer samples using deep sequencing

BACKGROUND: As hybrid RNAs, transcription-induced chimeras (TICs) may have tumor-promoting properties, and some specific chimeras have become important diagnostic markers and therapeutic targets for cancer. METHODS: We examined 23 paired laryngeal cancer (LC) tissues and adjacent normal mucous membr...

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Detalles Bibliográficos
Autores principales: Tao, Ye, Gross, Neil, Fan, Xiaojiao, Yang, Jianming, Teng, Maikun, Li, Xu, Li, Guojun, Zhang, Yang, Huang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834868/
https://www.ncbi.nlm.nih.gov/pubmed/29499655
http://dx.doi.org/10.1186/s12885-018-4161-8