Epigenomic Modifications Mediating Antibody Maturation

Epigenetic modifications, such as histone modifications, DNA methylation status, and non-coding RNAs (ncRNA), all contribute to antibody maturation during somatic hypermutation (SHM) and class-switch recombination (CSR). Histone modifications alter the chromatin landscape and, together with DNA prim...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheppard, Emily C., Morrish, Rikke Brandstrup, Dillon, Michael J., Leyland, Rebecca, Chahwan, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834911/
https://www.ncbi.nlm.nih.gov/pubmed/29535729
http://dx.doi.org/10.3389/fimmu.2018.00355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834911/
https://www.ncbi.nlm.nih.gov/pubmed/29535729
http://dx.doi.org/10.3389/fimmu.2018.00355

Ejemplares similares