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Epigenomic Modifications Mediating Antibody Maturation

Epigenetic modifications, such as histone modifications, DNA methylation status, and non-coding RNAs (ncRNA), all contribute to antibody maturation during somatic hypermutation (SHM) and class-switch recombination (CSR). Histone modifications alter the chromatin landscape and, together with DNA prim...

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Detalles Bibliográficos
Autores principales:	Sheppard, Emily C., Morrish, Rikke Brandstrup, Dillon, Michael J., Leyland, Rebecca, Chahwan, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834911/ https://www.ncbi.nlm.nih.gov/pubmed/29535729 http://dx.doi.org/10.3389/fimmu.2018.00355

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