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Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN

Hypoxia, the most commonly observed characteristic in cancers, is implicated in the establishment of an immunosuppressive niche. Recent studies have indicated that extracellular vesicle (EV)-mediated cancer-stroma interactions are considered to play a critical role in the regulation of various cellu...

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Detalles Bibliográficos
Autores principales: Hsu, Ya-Ling, Hung, Jen-Yu, Chang, Wei-An, Jian, Shu-Fang, Lin, Yi-Shiuan, Pan, Yi-Chung, Wu, Cheng-Ying, Kuo, Po-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835028/
https://www.ncbi.nlm.nih.gov/pubmed/29292163
http://dx.doi.org/10.1016/j.ymthe.2017.11.016