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Tissue Damage Caused by Myeloablative, but Not Non-Myeloablative, Conditioning before Allogeneic Stem Cell Transplantation Results in Dermal Macrophage Recruitment without Active T-Cell Interaction

INTRODUCTION: Conditioning regimens preceding allogeneic stem cell transplantation (alloSCT) can cause tissue damage and acceleration of the development of graft-versus-host disease (GVHD). T-cell-depleted alloSCT with postponed donor lymphocyte infusion (DLI) may reduce GVHD, because tissue injury...

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Detalles Bibliográficos
Autores principales: van Balen, Peter, van der Zouwen, Boris, Kruisselbrink, Alwine B., Eefting, Matthijs, Szuhai, Karoly, Jordanova, Ekaterina S., Falkenburg, J. H. F., Jedema, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835032/
https://www.ncbi.nlm.nih.gov/pubmed/29535719
http://dx.doi.org/10.3389/fimmu.2018.00331