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Telomerase Reverse Transcriptase Polymorphism rs2736100: A Balancing Act between Cancer and Non-Cancer Disease, a Meta-Analysis

The enzyme telomerase reverse transcriptase (TERT) is essential for telomere maintenance. In replicating cells, maintenance of telomere length is important for the preservation of vital genetic information and prevention of genomic instability. A common genetic variant in TERT, rs2736100 C/A, is ass...

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Detalles Bibliográficos
Autores principales: Snetselaar, Reinier, van Oosterhout, Matthijs F. M., Grutters, Jan C., van Moorsel, Coline H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835035/
https://www.ncbi.nlm.nih.gov/pubmed/29536006
http://dx.doi.org/10.3389/fmed.2018.00041