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Cell-Based Reporter System for High-Throughput Screening of MicroRNA Pathway Inhibitors and Its Limitations

MicroRNAs (miRNAs) are small RNAs repressing gene expression. They contribute to many physiological processes and pathologies. Consequently, strategies for manipulation of the miRNA pathway are of interest as they could provide tools for experimental or therapeutic interventions. One of such tools c...

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Detalles Bibliográficos
Autores principales: Brustikova, Katerina, Sedlak, David, Kubikova, Jana, Skuta, Ctibor, Solcova, Katerina, Malik, Radek, Bartunek, Petr, Svoboda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835079/
https://www.ncbi.nlm.nih.gov/pubmed/29535760
http://dx.doi.org/10.3389/fgene.2018.00045