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Cell-Based Reporter System for High-Throughput Screening of MicroRNA Pathway Inhibitors and Its Limitations
MicroRNAs (miRNAs) are small RNAs repressing gene expression. They contribute to many physiological processes and pathologies. Consequently, strategies for manipulation of the miRNA pathway are of interest as they could provide tools for experimental or therapeutic interventions. One of such tools c...
Autores principales: | Brustikova, Katerina, Sedlak, David, Kubikova, Jana, Skuta, Ctibor, Solcova, Katerina, Malik, Radek, Bartunek, Petr, Svoboda, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835079/ https://www.ncbi.nlm.nih.gov/pubmed/29535760 http://dx.doi.org/10.3389/fgene.2018.00045 |
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