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Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation

The lateral habenula has been widely studied for its contribution in generating reward-related behaviors [1, 2]. We have found that this nucleus plays an unexpected role in the sedative actions of the general anesthetic propofol. The lateral habenula is a glutamatergic, excitatory hub that projects...

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Detalles Bibliográficos
Autores principales: Gelegen, Cigdem, Miracca, Giulia, Ran, Mingzi Z., Harding, Edward C., Ye, Zhiwen, Yu, Xiao, Tossell, Kyoko, Houston, Catriona M., Yustos, Raquel, Hawkins, Edwin D., Vyssotski, Alexei L., Dong, Hailong L., Wisden, William, Franks, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835141/
https://www.ncbi.nlm.nih.gov/pubmed/29398217
http://dx.doi.org/10.1016/j.cub.2017.12.050