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Short-Term Treatment with Esmolol Reverses Left Ventricular Hypertrophy in Adult Spontaneously Hypertensive Rats via Inhibition of Akt/NF-κB and NFATc4

Our group has previously demonstrated that short-term treatment with esmolol reduces left ventricular hypertrophy (LVH) in spontaneously hypertensive rats (SHRs). The present study aimed to assess the molecular mechanisms related to this effect. Fourteen-month-old male SHR(s) were treated intravenou...

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Detalles Bibliográficos
Autores principales: Quintana-Villamandos, Begoña, Goukassian, David A., Sasi, Sharath P., Delgado-Baeza, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835291/
https://www.ncbi.nlm.nih.gov/pubmed/29670896
http://dx.doi.org/10.1155/2018/2691014