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Formulation in DDA-MPLA-TDB Liposome Enhances the Immunogenicity and Protective Efficacy of a DNA Vaccine against Mycobacterium tuberculosis Infection

Despite the vaccine Mycobacterium bovis Bacillus Calmette–Guérin is used worldwide, tuberculosis (TB) remains the first killer among infectious diseases. An effective vaccine is urgently required. DNA vaccine has shown prophylactic as well as therapeutic effects against TB, while its weak immunogeni...

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Detalles Bibliográficos
Autores principales: Tian, Maopeng, Zhou, Zijie, Tan, Songwei, Fan, Xionglin, Li, Longmeng, Ullah, Nadeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835323/
https://www.ncbi.nlm.nih.gov/pubmed/29535714
http://dx.doi.org/10.3389/fimmu.2018.00310