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Immaturity of insulin secretion by pancreatic islets isolated from one human neonate

Human β‐cells are functionally mature by the age of 1 year. The timeline and mechanisms of this maturation are unknown owing to the exceptional availability of testable tissue. Here, we report the first in vitro study of insulin secretion by islets from a 5‐day‐old newborn. Glucose was inefficient a...

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Detalles Bibliográficos
Autores principales: Henquin, Jean‐Claude, Nenquin, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835448/
https://www.ncbi.nlm.nih.gov/pubmed/28597607
http://dx.doi.org/10.1111/jdi.12701