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Immaturity of insulin secretion by pancreatic islets isolated from one human neonate
Human β‐cells are functionally mature by the age of 1 year. The timeline and mechanisms of this maturation are unknown owing to the exceptional availability of testable tissue. Here, we report the first in vitro study of insulin secretion by islets from a 5‐day‐old newborn. Glucose was inefficient a...
Autores principales: | Henquin, Jean‐Claude, Nenquin, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835448/ https://www.ncbi.nlm.nih.gov/pubmed/28597607 http://dx.doi.org/10.1111/jdi.12701 |
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