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P2Y(6) Receptors Regulate CXCL10 Expression and Secretion in Mouse Intestinal Epithelial Cells

In this study, we investigated the role of extracellular nucleotides in chemokine (KC, MIP-2, MCP-1, and CXCL10) expression and secretion by murine primary intestinal epithelial cells (IECs) with a focus on P2Y(6) receptors. qRT-PCR experiments showed that P2Y(6) was the dominant nucleotide receptor...

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Detalles Bibliográficos
Autores principales: Salem, Mabrouka, Tremblay, Alain, Pelletier, Julie, Robaye, Bernard, Sévigny, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835513/
https://www.ncbi.nlm.nih.gov/pubmed/29541027
http://dx.doi.org/10.3389/fphar.2018.00149