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Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan

Neonates and infants are more vulnerable to infections and show reduced responses to vaccination. Consequently, repeated immunizations are required to induce protection and early life vaccines against major pathogens such as influenza are yet unavailable. Formulating antigens with potent adjuvants,...

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Detalles Bibliográficos
Autores principales: Vono, Maria, Eberhardt, Christiane Sigrid, Mohr, Elodie, Auderset, Floriane, Christensen, Dennis, Schmolke, Mirco, Coler, Rhea, Meinke, Andreas, Andersen, Peter, Lambert, Paul-Henri, Mastelic-Gavillet, Beatris, Siegrist, Claire-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835515/
https://www.ncbi.nlm.nih.gov/pubmed/29541075
http://dx.doi.org/10.3389/fimmu.2018.00381