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Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi

This study evaluated the participation of host cell Rho-family GTPases and their effector proteins in the actin-dependent invasion by Trypanosoma cruzi extracellular amastigotes (EAs). We observed that all proteins were recruited and colocalized with actin at EA invasion sites in live or fixed cells...

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Detalles Bibliográficos
Autores principales: Bonfim-Melo, Alexis, Ferreira, Éden R., Mortara, Renato A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835522/
https://www.ncbi.nlm.nih.gov/pubmed/29541069
http://dx.doi.org/10.3389/fmicb.2018.00360