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AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

Nonalcoholic fatty liver disease is a highly prevalent component of disorders associated with disrupted energy homeostasis. Although dysregulation of the energy sensor AMP-activated protein kinase (AMPK) is viewed as a pathogenic factor in the development of fatty liver its role has not been directl...

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Detalles Bibliográficos
Autores principales: Boudaba, Nadia, Marion, Allison, Huet, Camille, Pierre, Rémi, Viollet, Benoit, Foretz, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835560/
https://www.ncbi.nlm.nih.gov/pubmed/29343420
http://dx.doi.org/10.1016/j.ebiom.2018.01.008