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Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease

We recently reported that progranulin (PGRN) is a novel regulator of glucocerebrosidase and its deficiency associates with Gaucher Diseases (GD) (Jian et al., 2016a; Jian et al., 2018). To isolate the relevant downstream molecules, we performed a whole genome microarray and mass spectrometry analysi...

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Detalles Bibliográficos
Autores principales: Jian, Jinlong, Chen, Yuehong, Liberti, Rossella, Fu, Wenyu, Hu, Wenhuo, Saunders-Pullman, Rachel, Pastores, Gregory M., Chen, Ying, Sun, Ying, Grabowski, Gregory A., Liu, Chuan-ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835567/
https://www.ncbi.nlm.nih.gov/pubmed/29396296
http://dx.doi.org/10.1016/j.ebiom.2018.01.022