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Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells

Dendritic cells (DCs) are key directors of tolerogenic and immunogenic immune responses. During the steady state, DCs maintain T cell tolerance to self-antigens by multiple mechanisms including inducing anergy, deletion, and Treg activity. All of these mechanisms help to prevent autoimmune diseases...

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Detalles Bibliográficos
Autores principales: Vendelova, Emilia, Ashour, Diyaaeldin, Blank, Patrick, Erhard, Florian, Saliba, Antoine-Emmanuel, Kalinke, Ulrich, Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835767/
https://www.ncbi.nlm.nih.gov/pubmed/29541071
http://dx.doi.org/10.3389/fimmu.2018.00333