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Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells
Dendritic cells (DCs) are key directors of tolerogenic and immunogenic immune responses. During the steady state, DCs maintain T cell tolerance to self-antigens by multiple mechanisms including inducing anergy, deletion, and Treg activity. All of these mechanisms help to prevent autoimmune diseases...
Autores principales: | Vendelova, Emilia, Ashour, Diyaaeldin, Blank, Patrick, Erhard, Florian, Saliba, Antoine-Emmanuel, Kalinke, Ulrich, Lutz, Manfred B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835767/ https://www.ncbi.nlm.nih.gov/pubmed/29541071 http://dx.doi.org/10.3389/fimmu.2018.00333 |
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