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High expression of PRPS1 induces an anti-apoptotic effect in B-ALL cell lines and predicts an adverse prognosis in Chinese children with B-ALL

Phosphoribosyl pyrophosphate synthetase 1 (PRPS1) is closely associated with a number of diseases; however, its influence in B-cell acute lymphoblastic leukemia (B-ALL) and the potential molecular mechanisms involved remain unclear. The present study aimed to evaluate the expression of PRPS1 in Chin...

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Detalles Bibliográficos
Autores principales: Ma, Yimei, An, Xizhou, Guan, Xianmin, Kong, Qinglin, Wang, Yanzhen, Li, Pengfei, Meng, Yan, Cui, Yinghui, Wen, Xianhao, Guo, Yuxia, Shen, Yali, Yu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835884/
https://www.ncbi.nlm.nih.gov/pubmed/29541198
http://dx.doi.org/10.3892/ol.2018.7903