LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2

The ‘Warburg effect’ is considered a vital hallmark of cancer cells, characterized by an altered metabolism, in which cells rely on aerobic glycolysis. As a key enzyme of aerobic glycolysis, pyruvate kinase M2 (PKM2) serves a crucial role in tumorigenesis. Accumulating studies have indicated that PK...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Jian, Chen, Min, Gao, Sumeng, Yuan, Jigang, Zhu, Zhu, Zou, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835956/
https://www.ncbi.nlm.nih.gov/pubmed/29541204
http://dx.doi.org/10.3892/ol.2018.7843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835956/
https://www.ncbi.nlm.nih.gov/pubmed/29541204
http://dx.doi.org/10.3892/ol.2018.7843

Ejemplares similares