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Autophagy flux inhibition augments gastric cancer resistance to the anti-human epidermal growth factor receptor 2 antibody trastuzumab

The autophagy involved in the occurrence, development and prognosis of human epidermal growth factor receptor 2 (HER2) gene-amplified cancer also controls the resistance of this type of cancer to the monoclonal antibody, trastuzumab (Tzb). In the present study, Tzb resistance was established in HER2...

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Detalles Bibliográficos
Autores principales: Ye, Hua, Chai, Xuyu, Wang, Xiaoyu, Zheng, Qi, Zheng, Dingcheng, Wu, Feng, Zheng, Cheng, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835962/
https://www.ncbi.nlm.nih.gov/pubmed/29541179
http://dx.doi.org/10.3892/ol.2018.7891