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Phosphorylation of Sox2 at Threonine 116 is a Potential Marker to Identify a Subset of Breast Cancer Cells with High Tumorigenecity and Stem-Like Features

We have previously identified a novel phenotypic dichotomy in breast cancer (BC) based on the response to a SRR2 (Sox2 regulatory region 2) reporter, with reporter responsive (RR) cells being more tumorigenic/stem-like than reporter unresponsive (RU) cells. Since the expression level of Sox2 is comp...

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Detalles Bibliográficos
Autores principales: Gupta, Nidhi, Gopal, Keshav, Wu, Chengsheng, Alshareef, Abdulraheem, Chow, Alexandra, Wu, Fang, Wang, Peng, Ye, Xiaoxia, Bigras, Gilbert, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836073/
https://www.ncbi.nlm.nih.gov/pubmed/29401647
http://dx.doi.org/10.3390/cancers10020041