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Next Generation Immunotherapy for Pancreatic Cancer: DNA Vaccination is Seeking New Combo Partners

Pancreatic Ductal Adenocarcinoma (PDA) is an almost incurable radio- and chemo-resistant tumor, and its microenvironment is characterized by a strong desmoplastic reaction associated with a significant infiltration of T regulatory lymphocytes and myeloid-derived suppressor cells (Tregs, MDSC). Inves...

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Detalles Bibliográficos
Autores principales: Cappello, Paola, Curcio, Claudia, Mandili, Giorgia, Roux, Cecilia, Bulfamante, Sara, Novelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836083/
https://www.ncbi.nlm.nih.gov/pubmed/29462900
http://dx.doi.org/10.3390/cancers10020051