A Phase I/II Study Targeting Angiogenesis Using Bevacizumab Combined with Chemotherapy and a Histone Deacetylase Inhibitor (Valproic Acid) in Advanced Sarcomas

Epigenetic events and genetic alterations under the control of the tumor microenvironment potentially mediate tumor induced angiogenesis involved in soft tissue sarcoma (STS) metastasis. Addition of antiangiogenic agent, such as bevacizumab, to standard chemotherapy in treatment of sarcoma has been...

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Detalles Bibliográficos
Autores principales: Monga, Varun, Swami, Umang, Tanas, Munir, Bossler, Aaron, Mott, Sarah L., Smith, Brian J., Milhem, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836085/
https://www.ncbi.nlm.nih.gov/pubmed/29462961
http://dx.doi.org/10.3390/cancers10020053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836085/
https://www.ncbi.nlm.nih.gov/pubmed/29462961
http://dx.doi.org/10.3390/cancers10020053

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