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Cancer Stem Cells, Bone and Tumor Microenvironment: Key Players in Bone Metastases

Tumor mass is constituted by a heterogeneous group of cells, among which a key role is played by the cancer stem cells (CSCs), possessing high regenerative properties. CSCs directly metastasize to bone, since bone microenvironment represents a fertile environment that protects CSCs against the immun...

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Detalles Bibliográficos
Autores principales: Roato, Ilaria, Ferracini, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836088/
https://www.ncbi.nlm.nih.gov/pubmed/29461491
http://dx.doi.org/10.3390/cancers10020056