PNLDC1, mouse pre‐piRNA Trimmer, is required for meiotic and post‐meiotic male germ cell development

PIWI‐interacting RNAs (piRNAs) are germ cell‐specific small RNAs essential for retrotransposon gene silencing and male germ cell development. In piRNA biogenesis, the endonuclease MitoPLD/Zucchini cleaves long, single‐stranded RNAs to generate 5′ termini of precursor piRNAs (pre‐piRNAs) that are con...

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Detalles Bibliográficos
Autores principales: Nishimura, Toru, Nagamori, Ippei, Nakatani, Tsunetoshi, Izumi, Natsuko, Tomari, Yukihide, Kuramochi‐Miyagawa, Satomi, Nakano, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836094/
https://www.ncbi.nlm.nih.gov/pubmed/29444933
http://dx.doi.org/10.15252/embr.201744957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836094/
https://www.ncbi.nlm.nih.gov/pubmed/29444933
http://dx.doi.org/10.15252/embr.201744957

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