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PNLDC1, mouse pre‐piRNA Trimmer, is required for meiotic and post‐meiotic male germ cell development
PIWI‐interacting RNAs (piRNAs) are germ cell‐specific small RNAs essential for retrotransposon gene silencing and male germ cell development. In piRNA biogenesis, the endonuclease MitoPLD/Zucchini cleaves long, single‐stranded RNAs to generate 5′ termini of precursor piRNAs (pre‐piRNAs) that are con...
Autores principales: | Nishimura, Toru, Nagamori, Ippei, Nakatani, Tsunetoshi, Izumi, Natsuko, Tomari, Yukihide, Kuramochi‐Miyagawa, Satomi, Nakano, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836094/ https://www.ncbi.nlm.nih.gov/pubmed/29444933 http://dx.doi.org/10.15252/embr.201744957 |
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