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Perturbing mitosis for anti‐cancer therapy: is cell death the only answer?

Interfering with mitosis for cancer treatment is an old concept that has proven highly successful in the clinics. Microtubule poisons are used to treat patients with different types of blood or solid cancer since more than 20 years, but how these drugs achieve clinical response is still unclear. Arr...

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Detalles Bibliográficos
Autores principales: Haschka, Manuel, Karbon, Gerlinde, Fava, Luca L, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836099/
https://www.ncbi.nlm.nih.gov/pubmed/29459486
http://dx.doi.org/10.15252/embr.201745440