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A protein interaction network centered on leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) regulates growth factor receptors

Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. The molecular mechanisms by which LRIG1 mediates its tumor suppressor effects and regulates receptor tyrosine kinases remain incompletely understood. He...

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Detalles Bibliográficos
Autores principales: Faraz, Mahmood, Herdenberg, Carl, Holmlund, Camilla, Henriksson, Roger, Hedman, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836135/
https://www.ncbi.nlm.nih.gov/pubmed/29317492
http://dx.doi.org/10.1074/jbc.M117.807487