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Strategies to Advance Drug Discovery in Rare Monogenic Intellectual Disability Syndromes

Some intellectual disability syndromes are caused by a mutation in a single gene and have been the focus of therapeutic intervention attempts, such as Fragile X and Rett Syndrome, albeit with limited success. The rate at which new drugs are discovered and tested in humans for intellectual disability...

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Detalles Bibliográficos
Autores principales: Hettige, Nuwan C, Manzano-Vargas, Karla, Jefri, Malvin, Ernst, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836272/
https://www.ncbi.nlm.nih.gov/pubmed/29040584
http://dx.doi.org/10.1093/ijnp/pyx090