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T-614 Promotes Osteoblastic Cell Differentiation by Increasing Dlx5 Expression and Regulating the Activation of p38 and NF-κB

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by bone loss. Degree of inflammation has been identified as an important initiator of skeletal damage in RA. Iguratimod (T-614) is an anti-inflammatory agent which has been reported to show the inhibitory effect of bone de...

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Detalles Bibliográficos
Autores principales: Song, Jinglue, Liu, Hongli, Zhu, Qi, Miao, Yutong, Wang, Feiyan, Yang, Fan, Cheng, Wenjing, Xi, Yebin, Niu, Xiaoyin, He, Dongyi, Chen, Guangjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836304/
https://www.ncbi.nlm.nih.gov/pubmed/29670900
http://dx.doi.org/10.1155/2018/4901591