Cargando…

T-614 Promotes Osteoblastic Cell Differentiation by Increasing Dlx5 Expression and Regulating the Activation of p38 and NF-κB

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by bone loss. Degree of inflammation has been identified as an important initiator of skeletal damage in RA. Iguratimod (T-614) is an anti-inflammatory agent which has been reported to show the inhibitory effect of bone de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Jinglue, Liu, Hongli, Zhu, Qi, Miao, Yutong, Wang, Feiyan, Yang, Fan, Cheng, Wenjing, Xi, Yebin, Niu, Xiaoyin, He, Dongyi, Chen, Guangjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836304/ https://www.ncbi.nlm.nih.gov/pubmed/29670900 http://dx.doi.org/10.1155/2018/4901591

Ejemplares similares

Regulatory Effect of Iguratimod on the Balance of Th Subsets and Inhibition of Inflammatory Cytokines in Patients with Rheumatoid Arthritis
por: Xu, Yunzhi, et al.
Publicado: (2015)

Estrogen Receptor α Regulates Dlx3-Mediated Osteoblast Differentiation
por: Lee, Sung Ho, et al.
Publicado: (2016)

T Cell Vaccination Inhibits Th1/Th17/Tfh Frequencies and Production of Autoantibodies in Collagen-Induced Arthritis
por: Li, Shan, et al.
Publicado: (2013)

The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1β and NF-κB signaling
por: Trinh, Bon Q., et al.
Publicado: (2015)

Inhibition of Osteoblast Functions by IKK/NF-κB in Osteoporosis
por: Chang, Jia, et al.
Publicado: (2009)

Different Methylation Patterns of RUNX2, OSX, DLX5 and BSP in Osteoblastic Differentiation of Mesenchymal Stem Cells
por: Farshdousti Hagh, Majid, et al.
Publicado: (2015)

Dlx5 and Dlx6 can antagonize cell division at the G(1)/S checkpoint
por: MacKenzie, Rachel K., et al.
Publicado: (2019)

Rocaglamide-A Potentiates Osteoblast Differentiation by Inhibiting NF-κB Signaling
por: Li, Aiguo, et al.
Publicado: (2015)

Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border
por: Narboux-Neme, Nicolas, et al.
Publicado: (2019)

Increased Sociability in Mice Lacking Intergenic Dlx Enhancers
por: Fazel Darbandi, Siavash, et al.
Publicado: (2021)

Clinical Biomarkers and Pathogenic-Related Cytokines in Rheumatoid Arthritis
por: Niu, Xiaoyin, et al.
Publicado: (2014)

DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex
por: Miyano, Masaru, et al.
Publicado: (2008)

Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan
por: de Lombares, Camille, et al.
Publicado: (2019)

DLX Genes: Roles in Development and Cancer
por: Tan, Yinfei, et al.
Publicado: (2021)

Transitory expression of Dlx5 and Dlx6 in maxillary arch epithelial precursors is essential for upper jaw morphogenesis
por: Gitton, Yorick, et al.
Publicado: (2014)

p38 MAPK Signaling in Osteoblast Differentiation
por: Rodríguez-Carballo, Eddie, et al.
Publicado: (2016)

Melatonin Promotes BMSCs Osteoblastic Differentiation and Relieves Inflammation by Suppressing the NF-κB Pathways
por: Hu, Yiqiang, et al.
Publicado: (2023)

Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina
por: Zhang, Qi, et al.
Publicado: (2017)

Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in golden Syrian hamster
por: Brustolin, Marco, et al.
Publicado: (2021)

DLX, the multiprocessor assembly for LEP/SPS controls
por: Van der Stok, P D V
Publicado: (1990)

Non-parsimonious evolution of hagfish Dlx genes
por: Fujimoto, Satoko, et al.
Publicado: (2013)

Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification
por: Zhu, Hui, et al.
Publicado: (2009)

Loss of dlx5a/dlx6a Locus Alters Non-Canonical Wnt Signaling and Meckel’s Cartilage Morphology
por: Yu, Emily P. Y., et al.
Publicado: (2023)

The virological impacts of SARS-CoV-2 D614G mutation
por: Wang, Chenxi, et al.
Publicado: (2021)

Extracellular S100A4 negatively regulates osteoblast function by activating the NF-κB pathway
por: Kim, Haemin, et al.
Publicado: (2017)

Stability of SARS-CoV-2 Spike G614 Variant Surpasses That of the D614 Variant after Cold Storage
por: Huang, Sheng-Yu, et al.
Publicado: (2021)

Promoter methylation and expression pattern of DLX3, ATF4, and FRA1 genes during osteoblastic differentiation of adipose-derived mesenchymal stem cells
por: Rahimzadeh, Sevda, et al.
Publicado: (2020)

RAGE Silencing Ameliorates Neuroinflammation by Inhibition of p38-NF-κB Signaling Pathway in Mouse Model of Parkinson’s Disease
por: Wang, Xiaoli, et al.
Publicado: (2020)

Biosensing Detection of the SARS-CoV-2 D614G Mutation
por: Zhang, Yang, et al.
Publicado: (2021)

BMP-Mediated Functional Cooperation between Dlx5;Dlx6 and Msx1;Msx2 during Mammalian Limb Development
por: Vieux-Rochas, Maxence, et al.
Publicado: (2013)

The dlx5a/dlx6a Genes Play Essential Roles in the Early Development of Zebrafish Median Fin and Pectoral Structures
por: Heude, Églantine, et al.
Publicado: (2014)

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways
por: Zuo, Chijian, et al.
Publicado: (2017)

The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells
por: Tsubaki, Masanobu, et al.
Publicado: (2020)

Analysis of four DLX homeobox genes in autistic probands
por: Hamilton, Steven P, et al.
Publicado: (2005)

Dental and periodontal phenotypes of Dlx2 overexpression in mice
por: Dai, Jiewen, et al.
Publicado: (2017)

Overexpression of Dlx2 leads to postnatal condyle degradation
por: Dai, Jiewen, et al.
Publicado: (2016)

Mutation D614G increases SARS-CoV-2 transmission
por: Arora, Prerna, et al.
Publicado: (2021)

614. Evaluating the Use of Dalbavancin for Off-Label Indications
por: Taylor, Katherine, et al.
Publicado: (2021)

The G614 pandemic SARS-CoV-2 variant is not more pathogenic than the original D614 form in adult Syrian hamsters
por: Stauft, Charles B., et al.
Publicado: (2021)

TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A
por: Trendelenburg, Anne Ulrike, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_nb0ptb57rcrpluel69q5i0pabs