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Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance

BACKGROUND: Apoptosis plays an important role in the development and homeostasis of multicellular organisms and its deregulation may result in many serious diseases, including cancer. Now it is clear that some oncogenic mutations disrupt apoptosis, leading to tumour initiation, progression or metast...

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Detalles Bibliográficos
Autores principales: Vazanova, Andrea, Jurecekova, Jana, Balharek, Tomas, Marcinek, Juraj, Stasko, Jan, Dzian, Anton, Plank, Lukas, Zubor, Pavol, Racay, Peter, Hatok, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836377/
https://www.ncbi.nlm.nih.gov/pubmed/29515335
http://dx.doi.org/10.1186/s12935-018-0528-9