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Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos
BACKGROUND: Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been reported that exogenous human growth hormone can enhance expression of downstream mediators in the growth hormone and insulin-like growth factor I (IGF-I) pathway and partially res...
Autores principales: | Tsai, Tzu-Chun, Shih, Chun-Che, Chien, Hsin-Ping, Yang, An-Hang, Lu, Jenn-Kan, Lu, Jen-Her |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836385/ https://www.ncbi.nlm.nih.gov/pubmed/29506474 http://dx.doi.org/10.1186/s12861-017-0161-1 |
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