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Epidermal growth factor-mediated Rab25 pathway regulates integrin β1 trafficking in colon cancer
BACKGROUND: Integrins play a critical role in carcinogenesis. Integrin β1 localization is regulated by the guanosine-5′-triphosphate hydrolase Rab25 and integrin β1 levels are elevated in the serum of colon cancer patients; thus, the present study examined the effects of epidermal growth factor (EGF...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836438/ https://www.ncbi.nlm.nih.gov/pubmed/29515334 http://dx.doi.org/10.1186/s12935-018-0526-y |