Pharmacological inhibition of EZH2 disrupts the female germline epigenome

BACKGROUND: Recently discovered drugs that target epigenetic modifying complexes are providing new treatment options for a range of cancers that affect patients of reproductive age. Although these drugs provide new therapies, it is likely that they will also affect epigenetic programming in sperm an...

Descripción completa

Detalles Bibliográficos
Autores principales: Prokopuk, Lexie, Hogg, Kirsten, Western, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836460/
https://www.ncbi.nlm.nih.gov/pubmed/29515677
http://dx.doi.org/10.1186/s13148-018-0465-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836460/
https://www.ncbi.nlm.nih.gov/pubmed/29515677
http://dx.doi.org/10.1186/s13148-018-0465-4

Ejemplares similares