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Pharmacological inhibition of EZH2 disrupts the female germline epigenome
BACKGROUND: Recently discovered drugs that target epigenetic modifying complexes are providing new treatment options for a range of cancers that affect patients of reproductive age. Although these drugs provide new therapies, it is likely that they will also affect epigenetic programming in sperm an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836460/ https://www.ncbi.nlm.nih.gov/pubmed/29515677 http://dx.doi.org/10.1186/s13148-018-0465-4 |